The goal of this course is to combine theory introduced in previous courses with an understanding of how modern research endeavours are approached. This goal will be achieved by linking lectures and laboratories to contemporary research in molecular aspects of microbial physiology. Lectures will address molecular mechanisms involved in: determining microbial cell shape, cell division, sensing and responding to environmental signals, strategies for survival in extreme and stressful environments, and regulation of the synthesis of gene products. The lecture series also contains a module outlining the commercialisation of scientific discoveries. The practical program involves planning and implementing a research project in consultation with the course supervisor. Students will be challenged to identify relevant research problems, to generate feasible solutions to these problems, and to carry out critical peer review. The research training through lectures and practicals provides a solid basis for undertaking research in the Honours year.