This course takes students to the frontiers of immunological knowledge, exploring conflicting theories of immunological function and regulation, and highlighting new therapeutic strategies that build upon a knowledge of immunology. Students are also introduced to research techniques ranging from the use of knockout and transgenic animals to mathematical modelling. In addition, major topics of study include the immunogenetics of the molecules of recognition, cytokines and their regulation and lymphocyte biology. Issues arising from the public debate surrounding vaccination are an additional major focus of this course.