This course deals with quantitative and qualitative aspects of decision making, management options, ambiguity and sufficiency of evidence at the test-treatment threshold, identification of possible outcomes, calculation of probabilities and utilities for each outcome. It introduces structuring with decision analysis, elicitation of patients' preferences, configuration of trade-offs and sensitivity analysis, influences operating in the context and in the personal psychology of doctor and patient. The notions of defensibility of decisions, and judgement in making choices under uncertainty are also explored. Assignments include the analysis of a number of decision processes in the candidate's setting.