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Design & Analysis of Clinical Trials - MATH5906
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Faculty: Faculty of Science
 
 
School:  School of Mathematics and Statistics
 
 
Course Outline: http://www.maths.unsw.edu.au/
 
 
Campus: Kensington Campus
 
 
Career: Postgraduate
 
 
Units of Credit: 6
 
 
EFTSL: 0.12500 (more info)
 
 
Indicative Contact Hours per Week: 3
 
 
Fee Band: 2 (more info)
 
 
Further Information: See Class Timetable
 
 

Description

Introduction to the basic philosophy and history of the randomized controlled trial. Key definitions and concepts such as the intention to treat principle. Distinctions between different types of trials, such as parallel group versus crossover trials, superiority versus equivalence trials, and different phases of drug trials. Methods of randomization. Sample size determination. Interim analyses and group sequential trials. Methods for longitudinal clinical trials. Methods for crossover trials. Meta-analysis. Surrogate outcomes. Extensive use will be made of the statistical computing language R in analysing real datasets.

Note: Course not offered every year - contact School for more information.

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© The University of New South Wales (CRICOS Provider No.: 00098G), 2004-2011. The information contained in this Handbook is indicative only. While every effort is made to keep this information up-to-date, the University reserves the right to discontinue or vary arrangements, programs and courses at any time without notice and at its discretion. While the University will try to avoid or minimise any inconvenience, changes may also be made to programs, courses and staff after enrolment. The University may also set limits on the number of students in a course.