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 Therapeutics and the Molecular Basis of Disease 2 - PHPH9118
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Campus: Kensington Campus
 
 
Career: Postgraduate
 
 
Units of Credit: 6
 
 
EFTSL: 0.125 (more info)
 
 
Contact Hours per Week: 0
 
 
Fee Band: 2 (more info)
 
 
Further Information: See Class Timetable
 
  

Description

This course is a continuation of the material covered in PHPH9107 and, like the previous course, aims to provide a basis for understanding the mechanisms involved in disordered physiology that underlies common disease states. The objective is to provide an understanding of those disorders that are amenable to correction or amelioration with drug therapy. It thus provides a rationale for drug design and utilization. The course consists of four main sections: immunology and diseases of immunity; infection, genetic disorders; and neoplasia. Immunology and diseases of immunity includes a review of normal immune system mechanisms (cells of the immune system, cytokines, histocompatibility antigens, and hypersensitivity reactions); mechanisms of autoimmune diseases, immunologic deficiency syndromes, other actual or suspected immune system diseases (e.g. amyloidosis). Infection includes a brief introduction to mircobiology, general principles of microbial pathogenesis, discussion of selected human infectious diseases. Genetic disorders includes a brief section on the new genetics , mutation, mendelian disorders, disorders with multifactorial inheritance, normal karyotype cytogenetic disorders, single-gene disorders with nonclassic inheritance, molecular diagnosis. Neoplasia includes definitions and nomenclature, characteristics of benign and malignant neoplasms, epidemiology, molecular basis of cancer, biology of tumour growth, carcinogenic agents and their cellular interactions, host defence mechanisms, clinical features of tumours. Aspect of molecular biology relevant to the preceding topics (e.g. gene therapy) will be discussed.

Note: The course is elective for programmes 5504, and 9060.

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© The University of New South Wales (CRICOS Provider No.: 00098G), 2004-2011. The information contained in this Handbook is indicative only. While every effort is made to keep this information up-to-date, the University reserves the right to discontinue or vary arrangements, programs and courses at any time without notice and at its discretion. While the University will try to avoid or minimise any inconvenience, changes may also be made to programs, courses and staff after enrolment. The University may also set limits on the number of students in a course.