Covers the aspects of metabolism that are of particular relevance to the human. The major topics covered will be selected from: nutrition, exercise, neurochemistry, xenobiotics, nucleotide and one-carbon metabolism, genetic diseases and molecular aspects of parasitology. The role of triglyceride, cholesterol and lipoprotein metabolism in human health, and other selected areas of human nutrition. Specialised aspects of endocrinology and neurochemistry including prostaglandins, leukotrienes, enkephalins and endorphins. The interrelation of purines, pyrimidines, folate and cobalamin metabolism in humans. Xenobiotics: the metabolism of foreign compounds by humans. Biochemical aspects of genetic disease including the use of recombinant DNA techniques for prenatal diagnosis and carrier detection. Molecular studies of malaria and other parasites of the human. The biochemistry of diabetes. Molecular aspects of cancer and its treatment. Practical work to amplify the lectures.